Dorota Ferenc


Department of Chemistry
Johannes Gutenberg-University Mainz
Duesbergweg 10-14, 55128 Mainz
Room 2.223/02-125
Phone (06131) 39-25356
E-mail ferenc[at]
Research interests: synthetic organic chemistry

Six-Step Gram Scale Synthesis of the HIV Integrase Inhibitor Dolutegravir Sodium

J.-P. Dietz, T. Lucas, J. Groß, S. Seitel, J. Brauer, D. Ferenc, B. F. Gupton, T. Opatz, Org. Process Res. Dev. 2021, 25, 1898–1910.

Synthesis of 5-Fluorocytosine using 2-Cyano-2-fluoroethenolate as a Key Intermediate
J.-P. Dietz, B. P. Derstine, D. Ferenc, E. T. Crawford, A. J. Arduengo, III, B. F. Gupton, D. T. McQuade, T. Opatz, Eur. J. Org. Chem. 2019, 5519-5526.

Total Synthesis of (−)-Oxycodone via Anodic Aryl–Aryl Coupling
A. Lipp, M. Selt, D. Ferenc, D. Schollmeyer, S. R. Waldvogel, T. Opatz, Org. Lett. 2019, 21, 1828–1831.
(Cover Picture)
Article was highlighted in Nature Reviews Chemistry and Synfacts.

A Regio- and Diastereoselective Anodic Aryl-Aryl-Coupling in the Biomimetic Total Synthesis of (–)-Thebaine
A. Lipp, D. Ferenc, C. Gütz, M. Geffe, N. Vierengel, D. Schollmeyer, H. J. Schäfer, S. R. Waldvogel, T. Opatz,
Angew. Chem. Int. Ed.
2018, 57, 11055-11059. (VIP manuscript) (Cover picture)
Angew. Chem. 2018, 130, 11221-11225. (VIP-Manuskript) (Titelbild)

A Modular Access to (+/-)-Tubocurine and (+/-)-Curine - Formal Total Synthesis of Tubocurarine
N. Otto, D. Ferenc, T. Opatz, J. Org. Chem. 2017, 82, 1205–1217.

Chemoenzymatic Synthesis of Functional Sialyl Lewisx-Mimetics with a Heteroaromatic Core
C. Schlemmer, C. Wiebe, D. Ferenc, D. Kowalczyk, S. Wedepohl, P. Ziegelmüller, J. Dernedde, T. Opatz, Chem. Asian J. 2014, 9, 2119-2125.Simple Two-Step Synthesis of 2,4-Disubstituted Pyrroles and 3,5-Disubstituted Pyrrole-2-carbonitriles from Enones
M. Kücükdisli, D. Ferenc, M. Heinz, C. Wiebe, T. Opatz, Beilstein J. Org. Chem. 2014, 10, 466-470.Z-Amino(2-methyl-3-oxoisoindolin-1-ylidene)acetonitrile
D. Schollmeyer, D. Ferenc, T. Opatz, Acta Cryst. 2009, E65, o3024.Synthesis of the CDK-Inhibitor Paullone by Cyclization of a Deprotonated
T. Opatz, D. Ferenc, Synthesis 2008, 3941-3944.

Preparation of indoles from α-aminonitriles: a short synthesis of FGIN-1-27
T. Opatz, D. Ferenc. Org. Lett. 2006, 8, 4473-447.

Ring contracting rearrangements of 3-amino-4-(arylamino)-1H-isochromen-1-ones
T. Opatz, D. Ferenc, Eur. J. Org. Chem. 2006, 121-126.

Facile preparation of 3-amino-4-(arylamino)-1H-isochromen-1-ones by a
new multicomponent reaction

T. Opatz, D. Ferenc, Eur. J. Org. Chem. 2005, 817-821.

An unexpected three-component condensation leading to amino-(3-oxo-2,3-dihydro-1H-isoindol-1-ylidene)-acetonitriles
T. Opatz, D. Ferenc, J. Org. Chem. 2004, 69, 8496-8499.