Dr. Jonathan Groß



Department of Chemistry
Johannes Gutenberg-University Mainz
Duesbergweg 10-14, 55128 Mainz
Room 2.223/02-124
Phone (06131) 39-22288
E-mail jgross03[at]uni-mainz.de

Research interests: Green chemistry, xylochemistry, computational chemistry, VCD and ECD spectroscopy

Reversible oxidative dimerization of 4-thiouridines in tRNA isolates

L. Bessler, J. Groß, C. J. Kampf, T. Opatz, M. Helm, RSC Chem. Biol., 2024, Advance Article.

Structure elucidation and biological activities of perylenequinones from an Alternaria species

A. Kiefer, M. Arnholdt, V. Grimm, L. Geske, J. Groß, N. Vierengel, T. Opatz, G. Erkel, Mycotoxin Res., 2023, 39, 303-316.

An In Vitro Study of Local Oxygen Therapy as Adjunctive Antimicrobial Therapeutic Option for Patients with Periodontitis

L. K. Müller-Heupt, A. Eckelt, J. Eckelt, J. Groß, T. Opatz, N. Kommerein, Antibiotics, 2023, 12(6), 990.

Comparison of Different Density Functional Theory Methods for the Calculation of Vibrational Circular Dichroism Spectra

J. Groß, J. Kühlborn, S. Pusch, C. Weber, L. Andernach, G. Renzer, P. Eckhardt, J. Brauer, T. Opatz, Chirality, 2023, 1-13.

Diplomeroterpenoid G: An unusual meroterpenoid from Mimosa pudica Linn. (Mimosaceae)

C. F. Kenmogne, P. Eckhardt, R. T. Tchuenguem, J. Groß, F. T. Ngouafong, B. K. Ponou, J. P. Dzoyem, R. B. Teponno, T. Opatz, L. A. Tapondjou, Tetrahedron, 2023, 120, 154451.

Oxygen-Releasing Hyaluronic-Acid Based Dispersion with Controlled Oxygen Delivery for Enhanced Periodontal Tissue Engineering

L. K. Müller-Heupt, N. Wiesmann-Imilowski, S. Schröder, J. Groß, P. C. Ziskoven, P. Bani, P. W. Kämmerer, E. Schiegnitz, A. Eckelt, J. Eckelt, U. Ritz, T. Opatz, B. Al-Nawas, C. Synatschke, J. Deschner, Int. J. Mol. Sci., 2023, 24, 5936.

Total Synthesis and Biological Evaluation of the Anti-Inflammatory (13R,14S,15R)-13-Hydroxy-14-deoxyoxacyclododecindione

K. Seipp, J. Groß, A. Kiefer, G. Erkel, T. Opatz, J. Nat. Prod., 2023, 86, 924–938.

Complementary Mechanochemical and Biphasic Approaches for the Synthesis of Organic Thiocyanates using Hexacyanoferrates as Non-Toxic Cyanide Sources

C. Grundke, J. Groß, N. Vierengel, J. Sirleaf, M. Schmitz, L. Krieger, T. Opatz, Org. Biomol. Chem., 2023, 21, 644-650.

Extracts of Rheum palmatum and Aloe vera Show Beneficial Properties for the Synergistic Improvement of Oral Wound Healing

L. K. Müller-Heupt, N. Wiesmann, S. Schröder, Y. Korkmaz, N. Vierengel, J. Groß, R. Dahm, J. Deschner, T. Opatz, J. Brieger, B. Al-Nawas, P. W. Kämmerer, Pharmaceutics, 2022, 14, 2060.

Ethyl Hydroxyethyl Cellulose—A Biocompatible Polymer Carrier in Blood

A. Eckelt, F. Wichmann, F. Bayer, J. Eckelt, J. Groß, T. Opatz, K. Jurk, C. Reinhardt, K. Kiouptsi, Int. J. Med. Sci., 2022, 23, 6432.

Constituents of Desmodium salicifolium (Poir.) DC (Fabaceae) with antifungal activity

A. P. T. Donkia, P. Eckhardt, B. T. Tsafack , R. T. Tchuenguem, J. Groß, B. K. Ponou, R. B. Teponno, J. P. Dzoyem, T. Opatz, L. Barboni, L. A. Tapondjou, Phytochem. Lett., 2022, 50, 100-105.

Sesquiterpene Lactones from Vernonia tufnelliae: Structural Features, Stereochemistry, and Biological Evaluation

G. Bitchagno, A. Schueffler, J. Groß, M. Krumb, P. Tané, T. Opatz, J. Nat. Prod., 2022, 85, 1681-1690.

Antiplanktonic and Antibiofilm Activity of Rheum palmatum against Streptococcus oralis and Porphyromonas gingivalis

N. Kommerein, N. Vierengel, J. Groß, T. Opatz, B. Al-Nawas, L. K. Müller-Heupt, Microorganisms, 2022, 10, 965.

Vinylcyclopropane [3+2] Cycloaddition with Acetylenic Sulfones Based on Visible Light Photocatalysis

A. Luque, J. Groß, T. J. B. Zähringer, C. Kerzig, T. Opatz, Chem. Eur. J., 2022, 28, e2021043.

Antimicrobial Activity of Eucalyptus globulus, Azadirachta indica, Glycyrrhiza glabra, Rheum palmatum Extracts and Rhein against Porphyromonas gingivalis
L. K. Müller-Heupt, N. Vierengel, J. Groß, T. Opatz, J. Deschner, F. D. von Loewenich, Antibiotics, 2022, 11, 186.

Xylochemicals and Where to Find Them

J. Groß, C. Grundke, J. Rocker, A. J. Arduengo III, T.Opatz, Chem. Commun. 2021, 57, 9979-9994.

Anti-inflammatory dihydroxanthones from a Diaporthe species
M. Rohr, U. Kauhl, J. Groß, T. Opatz, G. Erkel, Biol. Chem., 2022, 403, 89-101.

Six-Step Gram Scale Synthesis of the HIV Integrase Inhibitor Dolutegravir Sodium

J.-P. Dietz, T. Lucas, J. Groß, S. Seitel, J. Brauer, D. Ferenc, B. F. Gupton, T. Opatz, Org. Process Res. Dev. 2021, 25, 1898–1910.

C-28/C-30 oxidized cycloartanes from the leaves and twigs of Caloncoba dusenii Gilg

L. Zeufack Nguetsa, J. D. Simo Mpetga, G. T. M. Bitchagno, J. Delain Tadjuidje, J. Groß B.N. Lenta, T. Opatz, N. Sewald, M. Tene, Phytochem. Lett., 2021, 43, 145-149.

Diels-Alder Reaction of β-Fluoro-β-nitrostyrenes with Cyclic Dienes

S. A. Ponomarev, R. V. Larkovich, A. S. Aldoshin, A. A. Tabolin, S. L. Ioffe, J. Groß,, T. Opatz, V. G. Nenajdenko, Beilstein J. Org. Chem., 2021, 17283–292.

An insight into the synthesis of N-methylated polypeptides

J. Groß, , Polym. Chem., 2020, 11, 6919-6927.

Antimicrobial secondary metabolites from the medicinal plant Crinum glaucum A. Chev. (Amaryllidaceae)
B. Y. Kianfé, J. Kühlborn, R.T. Tchuenguem B. T. Tchegnitegni, B. K. Ponou, J. Groß, R. B.Teponno, J. P. Dzoyem, T. Opatz, L. A.Tapondjou, S. Afr. J. Bot, 2020, 161-166.

Applications of Xylochemistry from Laboratory to Industrial Scale
J. Groß, J. Kühlborn, T. Opatz, Green Chem. 2020, 22, 4411-4425.

Making Natural Products from Renewable Feedstocks: Back to the Roots?
J. Kühlborn, J. Groß, T. Opatz, Nat. Prod. Rep. 2019. Review.

Structure, Biosynthesis, and Bioactivity of Photoditritide from Photorhabdus temperata Meg1

L. Zhao, R. M. Awori, M. Kaiser, J. Groß, T. Opatz, H. B. Bode, J. Nat. Prod. 2019, 82, 3499-3503.

Synthesis of 2,3-Dihydro-4-Pyridones, 4-Quinolones and 2,3-Dihydro-4-Azocinones by Visible-Light Photocatalytic Aerobic Dehydrogenation
A. Sevenich, P. S. Mark, T. Behrendt, J. Groß, T. Opatz, Eur. J. Org. Chem. 2020, 1505–1514.
This article was selected as Very Important Paper and also appears in: Special Collection: Photochemical Synthesis and ChemSusChem Hot Topic: Sustainable Chemistry.

Xylochemical Synthesis of Cytotoxic 2-Aminophenoxazinone-Type Natural Products Through Oxidative Cross Coupling
J. Kühlborn, M. Konhäuser, J. Groß, P. Wich, T. Opatz, ACS Sustainable Chem. Eng. 2019, 7, 4414–4419.