Dr. Jonas Kühlborn

Institute of Organic Chemistry
Johannes Gutenberg-University Mainz
Duesbergweg 10-14, 55128 Mainz
Room 2.223/02-125
Phone (06131) 39-25356
E-mail jokuehlb[at]uni-mainz.de
Research interests: Green chemistry, xylochemistry, computational chemistry, natural product elucidation

Hepatoprotective effects of extracts, fractions and compounds from the stem bark of Pentaclethra  macrophylla Benth: Evidence from in vitro and in vivo studies

C. L. K. Bomgning, P. V. K. Sinda, B. K. Ponou, A. L. Fotio, M. K. Tsague, B. T. Tsafack, J. Kühlborn, E. P. Mbuyo-Nguelefack, R. B. Teponno, T. Opatz, L. A. Tapondjou, T. B. Nguelefack, Biomed. Pharmacother. 2021, 136, 111242.

Hantzsch Ester-mediated Photochemical Transformations in the Ketone Series: Remote C(sp3)−H Arylation and Cyclopentene Synthesis through Strain Release

J. Paternoga, J. Kühlborn, N. O. Rossdam, T. Opatz, J. Org. Chem., 2021, 86, 4 3232–3248.


Antimicrobial secondary metabolites from the medicinal plant Crinum glaucum A. Chev. (Amaryllidaceae)
B. Y. Kianfé, J. Kühlborn, R.T. Tchuenguem B. T. Tchegnitegni, B. K. Ponou, J. Groß, R. B.Teponno, J. P. Dzoyem, T. Opatz, L. A.Tapondjou, S. Afr. J. Bot, 2020, 161-166.

Applications of Xylochemistry from Laboratory to Industrial Scale
J. Groß, J. Kühlborn, T. Opatz, Green Chem. 2020, 22, 4411-4425.

Making Natural Products from Renewable Feedstocks: Back to the Roots?
J. Kühlborn, J. Groß, T. Opatz, Nat. Prod. Rep. 2019. Review.

New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and unexpected Prodrug Identification
P. Klein, P. Johé, A. Wagner, S. Jung, B. Engels, J. Kühlborn, S. Tenzer, U. Distler, W. Waigel, U. A. Hellmich, T. Opatz, T. Schirmeister, Molecules, 2020, 25, 1451.

Antisalmonellal Activities of Extracts, Fractions, Compounds and Semi-synthetic Flavonoid Derivatives from Tristemma hirtum P. Beauv (Melastomataceae)

J. N. Kenfack, D. T. Ngoudjou, B. K. Ponou, J. Kühlborn, B. T. Tsafack, R. B. Teponno, T. Opatz, L. Barboni, D. Gatsing, L. A. Tapondjou, Science Journal of Chemistry. 2020, 8, 48-58.

Photoredox-Catalyzed Four Component Reaction for the Synthesis of Complex Secondary Amines

L. M. Kammer, M. Krumb, B. Spitzbarth, B. Lipp, J. Kühlborn, J. Busold, O. M. Mulina, A. O. Terentev and T. Opatz, Org. Lett. 2020, 22, 3318−3322. (Back Cover)

Flavans and other chemical constituents of Crinum biflorum (Amaryllidaceae)
B. Y. Kianfé, R. B. Teponno, J. Kühlborn, R. T. Tchuenguem, B. K. Ponou, S. E. Helaly, J. P. Dzoyem, T. Opatz, L. A. Tapondjou, Biochem. Syst. Ecol. 2019, 87, 103953.

A new ursane-type triterpene oxoglucopyranoside from Crossopteryx febrifuga
M. Kayangar, R. N. Nono, J. Kühlborn, R. Tchuenguem, B. K. Ponou, K. Jenett-Siems, R. B. Teponno, J. P. Dzoyem, T. Opatz, M. F. Melzig, L. A. Tapondjou, Z. Naturforsch. C, 2019, 74, 289–293.

Valorisation of Cashew Nut Shell Liquid Phenolics in the Synthesis of UV Absorbers
K. Ngwira, J. Kühlborn, Q. Mgani, C. de Koning, T. Opatz, Eur. J. Org. Chem. 2019, 4778-4790.

Visible Light-Induced Sulfonylation/Arylation of Styrenes in a Double Radical Three-Component Photoredox Reaction
B. Lipp, L. M. Kammer, M. Kücükdisli, A. Luque, J. Kühlborn,
S. Pusch, G. Matulevičiūtė, D. Schollmeyer, A. Šačkus, T. Opatz, Chem. Eur. J. 2019, 8965–8969.
(Hot Paper) (cover picture)

Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage
T. Opatz, J. Kühlborn, C. B. De Koning, K. J. Ngwira, Q. A. Mgani, South African provisional patent application 2019  ZA2019/01514.

Xylochemical Synthesis of Cytotoxic 2-Aminophenoxazinone-Type Natural Products Through Oxidative Cross Coupling
J. Kühlborn, M. Konhäuser, J. Groß, P. Wich, T. Opatz, ACS Sustainable Chem. Eng. 2019, 7, 4414–4419.

Protective Effects of Extracts, Isolated Compounds from Desmodium uncinatum and Semi-Synthetic Isovitexin Derivatives against Lipid Peroxidation of Hepatocyte’s Membranes
B. T. Tsafack, C. L. K. Boming, J. Kühlborn, R. T. Fouedjou, B. K. Ponou, R. B. Teponno, A. L. Fotio, L. Barboni, T. Opatz, T. B. Nguelefack, L. A. Tapondjou, Adv. Biol. Chem. 2018, 8, 101-120.

Chemical constituents from Anthocleista liebrechtsiana De Wild & T. Durand (Loganiaceae)
F. T. Ngouafong, R. T. Tchuenguem, J. Kühlborn, B. K. Ponou, R. B. Teponno, J. P. Dzoyem, T. Opatz, L. A. Tapondjou, Biochem. Syst. Ecol. 2018, 81, 17-20.

Examples of Xylochemistry: Colorants and Polymers
J. Kühlborn, A.-K. Danner, H. Frey, R. Iyer, A. J. Arduengo III, T. Opatz, Green Chem. 2017, 19, 3780–3786.