2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004, older publications



Strain Release Chemistry of Photogenerated Small‐Ring‐Intermediates
A. Luque
, J. Paternoga, T. Opatz, Chem. Eur. J. 2020, accepted manuscript.


An insight into the synthesis of N-methylated polypeptides
J. Groß, , Polym. Chem., 2020, Accepted Manuscript


2-Cyano-2-fluoroethenolate Salts (CFES): Versatile Active Pharmaceutical Intermediates
T. Opatz, US-Patent 2020 20200262785.


A Concise Route to MK-4482 (EIDD-2801) from Cytidine
N. Vasudevan, G. Ahlqvist, C. P. McGeough, D. J. Paymode, F. S. P. Cardoso, T. Lucas, J.-P. Dietz, T. Opatz, T. F. Jamison, B. F. Gupton,D. R. Snead, Chem. Commun., 2020, Accepted Manuscript


Multivalency beats Complexity: A Study on the Cell Uptake of Carbohydrate Functionalized Nanocarriers to Dendritic Cells
M. Krumb, M. L. Frey, J. Langhanki, R. Forster, D. Kowalczyk, V. Mailänder, K. Landfester, T. Opatz, Cells, 2020, 2087.
This article is a contribution within the CRC1066 and appears in the special issue: Nanoparticles in Cancer Immunotherapy


Glucose as an eco‐friendly reductant in a one‐pot synthesis of 2,3‐dihydroquinazolin‐4(1H)‐ones
T. dos Santos, C.Grundke, T. Lucas, L. Großmann, G. C. Closoki, T. Opatz, Eur. J. Org. Chem., 2020, accepted manuscript.


Antimicrobial secondary metabolites from the medicinal plant Crinum glaucum A. Chev. (Amaryllidaceae)
B. Y. Kianfé, J. Kühlborn, R.T. Tchuenguem B. T. Tchegnitegni, B. K. Ponou, J. Groß, R. B.Teponno, J. P. Dzoyem, T. Opatz, L. A.Tapondjou, S. Afr. J. Bot, 2020, 161-166.


Total synthesis and biological evaluation of seven new anti-inflammatory oxacyclododecindione-type macrolactones
C. Weber, N. Vierengel, T. Walter, T. Behrendt, T. Lucas, G. Erkel and T. Opatz, Org. Biomol. Chem., 2020, accepted manuscript.


α-Aminonitriles: From Sustainable Preparation to Applications in Natural Product Synthesis
C.Grundke, N. Vierengel, T. Opatz, Chem. Rec. 2020, accepted manuscript. (DOI: 10.1002/tcr.202000066)


New Alkenylresorcinols with Cytotoxic and Antimicrobial Activities from the Leaves of Embelia schimperi
T. A. M. Togue, B. L. Ndontsa, G. T. M. Bitchagno, A. Schüffler, T. Opatz, P. Tane, M. Tene, Planta Med.2020, accepted manuscript


An Efficient Synthesis of Tenofovir (PMPA): A Key Intermediate Leading to Tenofovir-based HIV Medicines
B. P. DerstineJ. W. TomlinC. Peck J.-P. Dietz, B. T. HerreraF. CardosoD. J. Paymode, A. C. YueA. J. ArduengoT. OpatzD. SneadR. W. StringhamD. T. McQuadeB. F. Gupton, Org. Process Res. Dev., 2020, accepted manuscript.


Total Synthesis of a Partial Structure from Arabinogalactan and its Application for Allergy-Prevention
M. Krumb, M. Jäger, A. Voss, L. Immig, K. Peters, D. Kowalczyk, A. Bufe, T. Opatz, O. Holst, C. Vogel, M. Peters, Chem. Eur. J., 2020, accepted manuscript.


A new ceramide from the leaves of Lannea schimperi
R. T. Nguemo, R. Mbouangouere, G. T. M. Bitchagno, R. Tchuenguem, E. V. N.Temgoua, B. L. Ndontsa, J. S. Mpetga, T. Opatz, A. S. Ngouela, P. Tane, Nat. Prod. Res., 2020, accepted manuscript.


Applications of Xylochemistry from Laboratory to Industrial Scale
J. Groß, J. Kühlborn, T. Opatz, Green Chem. 2020, accepted article


Copper-catalyzed one-pot synthesis of 3-(N-heteroarenyl)acrylonitriles through radical conjugated addition of β-nitrostyrene to methylazaarenes

N. M. Moreira, L. S. R. Martelli, K. I. R. de Julio, J. Zukerman-Schpector, T. Opatz, A. G. Corrêa, Eur. J. Org. Chem., 2020, accepted manuscript.


Anodic Oxidation as an Enabling Tool for the Synthesis of Natural Products
L. Geske, E. Sato, T. Opatz, Synthesis, 2020, 52, 2781-2794.

Chemical constituents of the root wood of Erythrina sacleuxii and determination of the absolute configuration of suberectin
J.O. Ombito, G. Bojase, R.R.T. Majinda, I.B. Masesane, A. Schüffler, S. Pusch, C. Weber, T. Opatz, Bull. Chem. Soc. Ethiop., 2020, 34, 135-140.


Thoughts on What Chemists Can Contribute to Fighting SARS-CoV-2 - A Short Note on Hand Sanitizers, Drug Candidates and Outreach
T. Opatz, J. Senn-Bilfinger, C. Richert, Angew. Chem. Int. Ed.; Angew. Chem. , 2020, accepted manuscript.


Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases – Studies on Inhibition Mechanism and Kinetics
P. Klein, F. Barthels, P. Johe, A. Wagner, S. Tenzer, U. Distler, T. A. Le, P. Schmid, V. Engel, B. Engels, U. A. Hellmich, T. Opatz, T. Schirmeister, Molecules, 2020, 25, 2064.


Predicting 19 F NMR chemical shifts: A combined computational and experimental study of a trypasonomal oxidoreductase-inhibitor complex
J. C. B. Dietschreit, A. Wagner, T. Anh Le, P. Klein, H. Schindelin, T. Opatz, B. Engels, U. A. Hellmich, C. Ochsenfeld, Angew. Chem. Int. Ed. (DOI: 10.1002/anie.202000539); Angew. Chem. (DOI: 10.1002/ange.202000539), 2020, accepted manuscript.


New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and unexpected Prodrug Identification
P. Klein, P. Johé, A. Wagner, S. Jung, B. Engels, J. Kühlborn, S. Tenzer, U. Distler, W. Waigel, U. A. Hellmich, T. Opatz, T. Schirmeister, Molecules, 2020, 25, 1451.


Resolving Binding Events on the Multifunctional Human Serum Albumin

L. Wenskowsky, M. Wagner, J. Reusch, H. Schreuder, H. Matter, T. Opatz, S. M. Petry, ChemMedChem, 2020, 15, 738-743


Photoredox-Catalyzed Four Component Reaction for the Synthesis of Complex Secondary Amines

L. M. Kammer, M. Krumb, B. Spitzbarth, B. Lipp, J. Kühlborn, J. Busold, O. M. Mulina, A. O. Terentev and T. Opatz, Org. Lett. 2020, 22, 3318−3322. (Back Cover)


Synthesis of 4-Amino-5-fluoropyrimidines and 5-Amino-4-fluoropyrazoles from a β-Fluoroenolate Salt
T. Lucas, J.-P. Dietz, T. OpatzBeilstein J. Org. Chem. 2020, 16, 445–450.


Targeting of Immune Cells with Trimannosylated Liposomes

K. Wagener, M. Bros, M. Krumb, J. Langhanki, S. Pektor, M. Worm, M. Schinnerer, E. Montermann, M. Miederer, H. Frey, T. Opatz, F. Rösch, Adv. Therap.2020, 1900185


Erysacleuxins C and D, new isoflavones from the twigs of Erythrina sacleuxii Hua and their cytotoxic activity

J. O. Ombito, G. Bojase, R. R. T. Majinda, I. B. Masesane, A. Schüffler, T. Opatz, Arab. J. Chem. 2020, 13, 4019–4023.


Smooth Metal-free Photoinduced Preparation of Valuable 8-Arylxanthines
H. O. Abdulla, A. A. Amin, C. Raviola, T. Opatz, S. Protti, M. Fagnoni, Eur. J. Org. Chem. 2020, 1448–1452.


Synthesis of 2,3-Dihydro-4-Pyridones, 4-Quinolones and 2,3-Dihydro-4-Azocinones by Visible-Light Photocatalytic Aerobic Dehydrogenation
A. Sevenich, P. S. Mark, T. Behrendt, J. Groß, T. Opatz, Eur. J. Org. Chem. 2020, 1505–1514.
This article was selected as Very Important Paper and also appears in: Special Collection: Photochemical Synthesis and ChemSusChem Hot Topic: Sustainable Chemistry.



Structure, Biosynthesis, and Bioactivity of Photoditritide from Photorhabdus temperata Meg1

L. Zhao, R. M. Awori, M. Kaiser, J. Groß, T. Opatz, H. B. Bode, J. Nat. Prod. 2019, 82, 3499-3503.


Visible Light-Induced Cleavage of C–S bonds in Thioacetals and Thioketals with Iodine as a Photocatalyst
M. Krumb, L. M. Kammer, R. Forster, C. Grundke, T. Opatz, ChemPhotoChem. 20204, 101 – 104.
This article was selected as Very Important Paper and also appears in: Hot Topic: Photocatalysis and Special collection: Photochemical Synthesis. (Cover Picture)


Neo-clerodane diterpenoids from Conyza pyrrhopappa Sch.Bip. ex A.Rich
G. T. M. Bitchagno, A. Schüffler, M. Krumb, P. Tane, T. Opatz, Nat. Prod. Res. 2019, DOI: 10.1080/14786419.2019.1690490.


Caffeate and piperidine-3-ol derivatives from the stem bark of Cassia sieberiana
B. C. K. Atontsa, G. T. M. Bitchagno, J. D. S. Mpetga, B. E. N. Wamba, P. Nayim, R. T. Tchuenguem, R. R. Koagne, T. Opatz, V. Kuete, P. Tane, Nat. Prod. Res. 2019, DOI: 10.1080/14786419.2019.1684278.


Making Natural Products from Renewable Feedstocks: Back to the Roots?
J. Kühlborn, J. Groß, T. Opatz, Nat. Prod. Rep. 2019. Review.


A Copper-Catalyzed Synthesis of Pyrroles through Photochemically Generated Acylazirines
J. Paternoga, T. Opatz, Eur. J. Org. Chem. 2019, 7067-7078.


Chemical recycling of polyenaminones by transamination reaction via amino–enaminone polymerisation/depolymerisation
A. Zupanc, T. Kotnik, U. Štanfel, H. B. Žugelj, A. Kristl, A. Ručigaj, L. Matoh, D. Pahovnik, U. Grošelj, T. Opatz, F. Požgan, B. Štefane, E. Žagar, J. Svete, Eur. Polym. J. 2019, 121, 109282.


A new polyketide from the bark of Hypericum roeperianum Schimp. (Hypericaceae)
F. Damen, O. M. F. Demgne, G. T. M. Bitchagno, I. Celik, J. D. S. Mpetga, S. B. Tankeo, T. Opatz, V. Kuete, P. Tane, Nat. Prod. Res. 2019, DOI: 10.1080/14786419.2019.1677655.


Flavans and other chemical constituents of Crinum biflorum (Amaryllidaceae)
B. Y. Kianfé, R. B. Teponno, J. Kühlborn, R. T. Tchuenguem, B. K. Ponou, S. E. Helaly, J. P. Dzoyem, T. Opatz, L. A. Tapondjou, Biochem. Syst. Ecol. 2019, 87, 103953.


A new ursane-type triterpene oxoglucopyranoside from Crossopteryx febrifuga
M. Kayangar, R. N. Nono, J. Kühlborn, R. Tchuenguem, B. K. Ponou, K. Jenett-Siems, R. B. Teponno, J. P. Dzoyem, T. Opatz, M. F. Melzig, L. A. Tapondjou, Z. Naturforsch. C, 2019, 74, 289–293.


Saponin with antibacterial activity from the roots of Albizia adianthifolia
G. Sonfack, C. F. Tchinda, I. K. Simo, G. T. M. Bitchagno, B. K. Nganou, İ. Çelik, M. Tene, S. F. Görkem, T. Opatz, V. Penlap Beng, V. Kuete, P. Tane, Nat. Prod. Res. 2019, DOI: 10.1080/14786419.2019.1672689.


Noncovalent targeting of nanocarriers to immune cells with polyphosphoester-based surfactants in human blood plasma
J. Simon, K. N. Bauer, J. Langhanki, T. Opatz, V. Mailänder, K. Landfester, F. R. Wurm, Adv. Sci. 2019, 6, 1901199.


Anthocleistenolide B, a New Secoiridoid from Anthocleista liebrechtsiana De Wild & T. Durand
F. T. Ngouafong, R. T. Tchuenguem, J. Kühlborn, B. T. Tchegnitegni, B. K. Ponou, R. B. Teponno, J. P. Dzoyem, T. Opatz, L. A. Tapondjou, Advances in Biological Chemistry, 2019, 9, 135-142.


(±) Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp.
Y.-N. Shi, S. Pusch, Y.-M. Shi, C. Richter, J. G. Macia-Vicente, H. Schwalbe, M. Kaiser, T. Opatz, H. B. Bode, J. Org. Chem. 2019, 84, 11203-11209.


A Xylochemically-Inspired Synthesis of Lamellarin G Trimethyl Ether via an Enaminone Intermediate
R. Klintworth, C. de Koning, T. Opatz, J. Michael, J. Org. Chem. 2019, 84, 11025-11031.


Valorisation of Cashew Nut Shell Liquid Phenolics in the Synthesis of UV Absorbers
K. Ngwira, J. Kühlborn, Q. Mgani, C. de Koning, T. Opatz, Eur. J. Org. Chem. 2019, 4778-4790.


Synthesis of 5-Fluorocytosine using 2-Cyano-2-fluoroethenolate as a Key Intermediate
J.-P. Dietz, B. P. Derstine, D. Ferenc, E. T. Crawford, A. J. Arduengo, III, B. F. Gupton, D. T. McQuade, T. Opatz, Eur. J. Org. Chem. 2019, 5519-5526.


Chemical profiling of the synthetic cannabinoid MDMB-CHMICA: identification, assessment and stability study of synthesis-related impurities in seized and synthesized samples
S. Münster-Müller, S. Hansen, T. Opatz, R. Zimmermann, M. Pütz, Drug Test. Analysis 2019, 11, 1192-1206.


Halogenated 2,1,3-benzoxadiazoles as Potential Fluorescent Warheads for Covalent Protease Inhibitors
A. Kuznetsova, P. Klein, T. Opatz, Proceedings 2019, 9, 54.


Visible Light-Induced Sulfonylation/Arylation of Styrenes in a Double Radical Three-Component Photoredox Reaction
B. Lipp, L. M. Kammer, M. Kücükdisli, A. Luque, J. Kühlborn,
S. Pusch, G. Matulevičiūtė, D. Schollmeyer, A. Šačkus, T. Opatz, Chem. Eur. J. 2019, 8965–8969.
(Hot Paper) (cover picture)


HPMA-Based Nanocarriers for Effective Immune System Stimulation
S. Kramer, J. Langhanki, M. Krumb, T. Opatz, M. Bros, R. Zentel, Macromol. Biosci. 2019, 1800481.


Strecker Reactions with Hexacyanoferrates as non-toxic Cyanide Sources
C. Grundke, T. Opatz, Green. Chem. 2019, 21, 2362-2366.


Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage
T. Opatz, J. Kühlborn, C. B. De Koning, K. J. Ngwira, Q. A. Mgani, South African provisional patent application 2019  ZA2019/01514.


Visible Light Enables Aerobic Iodine Catalyzed Glycosylation
M. Krumb, T. Lucas, T. Opatz, Eur. J. Org. Chem. 2019, 4517-4521.
Front Cover of Issue 28.


Gold(II) Porphyrins in Photoinduced Electron Transfer Reactions
S. Preiß, A. Päpcke, L. Burkhardt, L. Großmann, S. Lochbrunner, M. Bauer, T. Opatz, K. Heinze,
Chem. Eur. J. 2019, 25, 5940-5949.


Total Synthesis of (−)-Oxycodone via Anodic Aryl–Aryl Coupling
A. Lipp, M. Selt, D. Ferenc, D. Schollmeyer, S. R. Waldvogel, T. Opatz, Org. Lett. 2019, 21, 1828–1831.
(Cover Picture)
Article was highlighted in Nature Reviews Chemistry and Synfacts.


Xylochemical Synthesis of Cytotoxic 2-Aminophenoxazinone-Type Natural Products Through Oxidative Cross Coupling
J. Kühlborn, M. Konhäuser, J. Groß, P. Wich, T. Opatz, ACS Sustainable Chem. Eng. 2019, 7, 4414–4419.


Inhibitor-induced dimerization of an essential oxidoreductase from African Trypanosomes
A. Wagner, T. A. Le, M. Brennich, P. Klein, N. Bader, E. Diehl, D. Paszek, A. K. Weickhmann, N. Dirdjaja, R. L. Krauth-Siegel, B. Engels, T. Opatz, H. Schindelin, U. A. Hellmich, Angew. Chem. 2019, 1313679-3683.


Bisbenzylisoquinoline Alkaloids
C. Weber, T. Opatz, The Alkaloids 2019, 81, 1-114.


Aromatic hydrocarbons as catalysts and mediators in photoinduced electron transfer reactions
B Lipp, T. Opatz, in Photochemistry, 46, The Royal Society of Chemistry, 2019, 370-394.



Photoredox-Alkenylation of Carboxylic Acids and Peptides: Synthesis of Covalent Enzyme Inhibitors
L. M. Kammer, B. Lipp, T. Opatz, J. Org. Chem., 2019, 84 (5), 2379–2392.
Article was selected for "ACS Editors' Choice" (View ACS LiveSlides presentation, Front Cover).


Total Synthesis of epi-Trichosetin
U. Kauhl, L. Andernach, T. Opatz, J. Org. Chem. 201883, 15170–15177.


Protective Effects of Extracts, Isolated Compounds from Desmodium uncinatum and Semi-Synthetic Isovitexin Derivatives against Lipid Peroxidation of Hepatocyte’s Membranes
B. T. Tsafack, C. L. K. Boming, J. Kühlborn, R. T. Fouedjou, B. K. Ponou, R. B. Teponno, A. L. Fotio, L. Barboni, T. Opatz, T. B. Nguelefack, L. A. Tapondjou, Adv. Biol. Chem. 2018, 8, 101-120.


A New Flavonol Glycoside from Tristemma hirtum (Melastomataceae)
J. N. Kenfack, B. K. Ponou, J. Kühlborn, R. B. Teponno, R. N. Nono, R. T. Fouedjou, T. Opatz, H. J. Park, L. A. Tapondjou, Nat. Prod. Sci. 2018, 24, 213-218.


TiO2 Nanoparticles Functionalized with Non-Innocent Ligands Allow Oxidative Photocyanation of Amines with Visible/Near-Infrared Photons
A. M. Nauth, E. Schechtel, R. Dören, W. Tremel, T. Opatz, J. Am. Chem. Soc., 2018, 140, 14169–14177.


Non-toxic Cyanide Sources and Cyanating Agents
A. M. Nauth, T. Opatz, Org. Biomol. Chem., 2018, 17, 11-23. (Cover picture).


Chemical constituents from Anthocleista liebrechtsiana De Wild & T. Durand (Loganiaceae)
F. T. Ngouafong, R. T. Tchuenguem, J. Kühlborn, B. K. Ponou, R. B. Teponno, J. P. Dzoyem, T. Opatz, L. A. Tapondjou, Biochem. Syst. Ecol. 2018, 81, 17-20.


Flow Photochemistry of Azosulfones – Application of "Sunflow"-Reactors
P. E. da Silva Júnior, H. I. M. Amin, A. M. Nauth, F. da Silva Emery, S. Protti, T. Opatz, ChemPhotoChem 2018, 2, 878-883.
Cover picture of Issue 10 of ChemPhotoChem 2018.


Synthesis of α-Aminonitriles using Aliphatic Nitriles, α-Amino Acids, and Hexacyanoferrate as Universally Applicable Non-Toxic Cyanide Sources
A. M. Nauth, T. Konrad, Z. Papadopulu, N. Vierengel, B. Lipp, T. Opatz, Green Chem. 2018, 20, 4217-4223. (Cover picture).


Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice
E. Pflimlin, M. Bielohuby, M. Korn, K. Breitschopf, M. Löhn, P. Wohlfart, A. Konkar, M. Podeschwa, F. Bärenz, A. Pfenninger, U. Schwahn, T. Opatz, M. Reimann, S. Petry, N. Tennagels, Cell Metab. 2018, 28, 217-227.


Prenylated isoflavones from the stem bark of Erythrina sacleuxii
J. O. Ombito, R. R.T. Majinda, I. B. Masesane, G. Bojase, A. Schüffler, Till Opatz, Phytochem Lett. 2018, 26, 110–114.


A Regio- and Diastereoselective Anodic Aryl-Aryl-Coupling in the Biomimetic Total Synthesis of (–)-Thebaine
A. Lipp, D. Ferenc, C. Gütz, M. Geffe, N. Vierengel, D. Schollmeyer, H. J. Schäfer, S. R. Waldvogel, T. Opatz,
Angew. Chem. Int. Ed.
2018, 57, 11055-11059. (VIP manuscript) (Cover picture)
Angew. Chem. 2018, 130, 11221-11225. (VIP-Manuskript) (Titelbild)


Synthesis of Lamellarin G Trimethyl Ether via von Miller-Plöchl-Type Cyclocondensation
V. C. Colligs, C. Dialer, T. Opatz, Eur. J. Org. Chem. 2018, 4064-4070.


Crystal Structure Analysis of a "Star-Shaped" Triazine Compound: A Combination of Single-Crystal Electron Diffraction and Powder X-Ray Diffraction
T. Gorelik, J. van de Streek, H. Meier, L. Andernach, T. Opatz, Acta Crystallogr. B 2018, 287-294.


Visible Light Driven Minisci-Type Reaction with N-Hydroxyphthalimide Esters
L. M. Kammer, A. Rahman, T. Opatz, Molecules 2018, 23, 764.


Visible Light Organophotoredox-catalyzed Synthesis of Horner Precursors
M. M. Nebe, D. Loeper, F. Fürmeyer, T. Opatz, Eur. J. Org. Chem. 2018, 2471-2476.


Recent Advances in the Synthesis of Piperidines: Functionalization of Preexisting Ring Systems
G.-Q. Liu, T. Opatz, Adv. Heterocycl. Chem. 2018, 125, 107–234.


Mechanism and cis/trans Selectivity of Vinylogous Nazarov-Type [6π] Photocyclizations
S. Pusch, A. Tröster, D. Lefrancois, P. Farahani, A. Dreuw, T. Bach, T. Opatz, J. Org. Chem. 2018, 83, 964–972.


Synthesis and Unusual NMR-Spectroscopic Behavior of a Strained Bicyclic Ammonium Salt
S. Pusch, D. Schollmeyer, T. Opatz, Eur. J. Org. Chem. 2018, 1204-1207. (Cover picture)


Identification and Characterization of a Single High-Affinity Fatty Acid Binding Site in Human Serum Albumin
L. Wenskowsky, H. Schreuder, V. Derdau, H. Matter, J. Volkmar, T. Opatz, S. Petry, Angew. Chem. 2018, 57, 1044–1048.




Silver Oxide Mediated Monotosylation of Poly(ethylene glycol): Heterobifunctional PEG via Polymer Desymmetrization
H. Pohlit, M. Worm, J. Langhanki, E. Berger-Nicoletti, T. Opatz, H. Frey, Macromolecules 2017, 50, 9196–9206.


Oxidation of Trialkylamines by BrCCl3—Scope, Applications and Mechanistic Aspects
A. M. Nauth, J. C. Orejarena Pacheco, S. Pusch, T. Opatz, Eur. J. Org. Chem. 2017, 6966–6974.


Polyethylene bio-degradation by caterpillars?
C. Weber, S. Pusch, T. Opatz, Curr. Biol. 2017, 27, R744-R745.


Phytotoxic dioxolanones are potential virulence factors in the infection process of Guignardia bidwellii
I. Buckel, L. Andernach, A. Schüffler, M. Piepenbring, T. Opatz, E. Thines, Sci. Rep. 2017, 7, 8926.


Examples of Xylochemistry: Colorants and Polymers
J. Kühlborn, A.-K. Danner, H. Frey, R. Iyer, A. J. Arduengo III, T. Opatz, Green Chem. 2017, 19, 3780–3786.


A New Member of the Fusaricidin Family – Structure Elucidation and Synthesis of Fusaricidin E
M. Reimann, L. P. Sandjo, L Antelo, E. Thines, I. Siepe, T. Opatz, Beilstein J. Org. Chem. 2017, 13, 1430–1438.


Modular De Novo Synthesis of Unsymmetrical BODIPY Dyes possessing four different Aryl Substituents
N. Netz, C. Díez-Poza, A. Barbero, T. Opatz, Eur. J. Org. Chem. 2017, 4580–4599.


Cytotoxicity of Secondary Metabolites from Dracaena viridiflora Engl & Krause and their Semisynthetic Analogues
R. B. Teponno, J. P. Dzoyem, R. N. Nono, U. Kauhl, L. P. Sandjo, L. A. Tapondjou, U. Bakowsky, T. Opatz, Rec. Nat. Prod. 2017, 11, 421–430.


Photo-Chromium: Sensitizer for Visible Light-Induced Oxidative C-H Bond Functionalization – Electron or Energy Transfer?
S. Otto, A. M. Nauth, E. Ermilov, N. Scholz, A. Friedrich, U. Resch-Genger, S. Lochbrunner, T. Opatz, K. Heinze, ChemPhotoChem 2017, 1, 344–349.
Cover picture of Issue 8.


The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through the KEAP1-NRF2/HO-1 pathway
C. Hong, J. Cao, C.-F. Wu, O. Kadioglu, A. Schüffler, U. Kauhl, S. M. Klauck, T. Opatz, E. Thines, T. Efferth, Sci. Rep. 2017, 7, 11551.


New Photochemical Approaches to the Bilobalide Core
J. Emsermann, T. Opatz, Eur. J. Org. Chem. 2017, 3362–3372.


Light-Induced Alkylation of (Hetero)aromatic Nitriles in a Transition Metal-Free C–C-Bond Metathesis
B. Lipp, A. Lipp, H. Detert, T. Opatz, Org. Lett. 2017, 19, 2054–2057.


Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibiton by the Chinese Herbal Remedy Free and Easy Wanderer
C. Hong, A. Schüffler, U. Kauhl, J. Cao, C.-F. Wu, T. Opatz, E. Thines, T. Efferth, Front. Pharmacol. 2017, 8, 181.


“Clickable PEG” via anionic copolymerization of ethylene oxide and glycidyl propargyl ether
J. Herzberger, D. Leibig, J. Langhanki, C. Moers, T. Opatz, H. Frey, Polym. Chem. 2017, 8, 1882–1887.


Bioconjugation of small molecules to RNA impedes its recognition by Toll-like receptor 7 (TLR7)
I. Hellmuth, I. Freund, J. Schlöder, S. Seidu-Larry, K. Thüring, K. Slama, J. Langhanki, S. Kaloyanova, T. Eigenbrod, M. Krumb, S. Röhm, K. Peneva, T. Opatz, H. Jonuleit, A. H. Dalpke, M. Helm, Front. Immunol. 2017, 8, 312.


Synthesis and Biological Evaluation of a D-Ring-contracted Analogue of Lamellarin D
V. C. Colligs, S. P. Hansen, D. Imbri, E.-J. Seo, O. Kadioglu, T. Efferth, T. Opatz, Bioorg. Med. Chem. 2017, 6137-6148.


An Asymmetric One-Pot Synthesis of (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol: A Key Component of Current HIV Protease Inhibitors
A. Sevenich, G.-Q. Liu, A. J. Arduengo III, B. F. Gupton, T. Opatz, J. Org. Chem. 2017, 82, 1218–1223.
Article was highlighted in: Synfacts 2017, 13, 0343.


A Modular Access to (+/-)-Tubocurine and (+/-)-Curine - Formal Total Synthesis of Tubocurarine
N. Otto, D. Ferenc, T. Opatz, J. Org. Chem. 2017, 82, 1205–1217.


Sunflow: Sunlight Drives Fast and Green Photochemical Flow Reactions in Simple Micro Capillary Reactors — Application to Photoredox- and H-Atom Transfer Chemistry
A. M. Nauth, A. Lipp, B. Lipp, T. Opatz, Eur. J. Org. Chem. 2017, 2099–2103.
Link to Video Abstract.


Synthesis of Piperidines and Dehydropiperidines: Construction of the Six-Membered Ring
M. M. Nebe, T. Opatz, Adv. Heterocycl. Chem. 2017, 122, 191–244.


Haloperoxidase mimicry by CeO2-x nanorods combats biofouling
K. Herget. P. Hubach, S. Pusch, P. Deglmann, H. Götz, T. E. Gorelik, I. A. Gural'skiy, F. Pfitzner, T. Link, S. Schenk, M. Panthöfer, V. Ksenofontov, U. Kolb, T. Opatz, R. André, W. Tremel
Adv. Mater. 2017, 29, 1603823.


ESI-MS2 and anti-inflammatory studies of cyclopropanic triterpenes. UPLC-ESI-MS and MS2 search of related metabolites from Donella ubanguiensis
L. P. Sandjo, M. V. P. dos Santos Nascimento, L. A. L. da Silva, A. C. M. Munhoz, L. A. E. Pollo, M. W. Biavatti, B. T. Ngadjui, T. Opatz, T. S. Fröde
Phytochem. Anal. 2017, 28, 27–41.


Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae
Stefan Jacob; Thomas Grötsch; Andrew J. Foster; Anja Schüffler; Patrick H. Rieger; Louis P. Sandjo; Johannes C. Liermann; Till Opatz; Eckhard Thines
Microbiology 2017, 163, 541–553.



Characterization of the synthetic cannabinoid MDMB-CHMCZCA
Carina Weber, Stefan Pusch, Dieter Schollmeyer, Sascha Münster-Müller, Michael Pütz and Till Opatz
Beilstein J. Org. Chem. 2016, 12, 2808–2815.


Anti-inflammatory Tetraquinane Diterpenoids from a Crinipellis species
Markus Rohr, Katharina Oleinikov, Mathias Jung, Louis P. Sandjo, Till Opatz, Gerhard Erkel
Bioorg. Med. Chem. 2016, 25, 514–522.


Absolute Configuration Determination of 2,3-Dihydro-1H,5H-pyrazolo-[1,2-a]pyrazoles using Chiroptical Methods at Different Wavelengths.
Eva Pušavec Kirar, Uroš Grošelj, Amalija Golobič, Franc Požgan, Stefan Pusch, Carina Weber, Lars Andernach, Bogdan Štefane, Till Opatz, Jurij Svete
J. Org. Chem. 2016, 81, 11802–11812.


Terphenyl Derivatives from Allantophomopsis lycopodina
Andernach, Lars; Sandjo, Louis; Liermann, Johannes; Schlämann, Ricardo; Richter, Christian; Ferner, Jan-Peter; Schwalbe, Harald; Schueffler, Anja; Thines, Eckhard; Opatz, Till
J. Nat. Prod. 2016, 79, 2718–2725.


Transition Metal-free Decarboxylative Photoredox Coupling of Carboxylic Acids and Alcohols with Aromatic Nitriles
B. Lipp, A. M. Nauth, T. Opatz
J. Org. Chem. 2016, 81, 6875-6882.


A Short and Modular Approach towards 3,5-Disubstituted Indolizidine Alkaloids
M. M. Nebe, S. Zinn, T. Opatz
Org. Biomol. Chem. 2016, 14, 7084-7091.


Total Synthesis of Phenanthroindolizidine Alkaloids by Combining Iodoaminocyclization with a Free Radical Cyclization
G.-Q. Liu, M. Reimann, T. Opatz
J. Org. Chem. 2016, 81, 6142-6148.


Secondary brown carbon formation via the dicarbonyl imine pathway: Nitrogen heterocycle formation and synergistic effects
C. J. Kampf, A. Filippi, C. Zuth, T. Hoffmann, T. Opatz
Phys. Chem. Chem. Phys. 2016, 18, 18353-18364.


A Light-Induced Vinylogous Nazarov-Type Cyclization
S. Pusch, D. Schollmeyer, T. Opatz
Org. Lett. 2016, 18, 3043-3045.


Separation, isolation and stereochemical assignment of imazalil enantiomers and their quantitation in an in vitro toxicity test
M. Escolà Casas, A. C. Kretschmann, L. Andernach, T. Opatz, K. Bester
J. Chromatogr. A 2016, 1452, 116-120.


Light Induced C–C Coupling of 2-Chlorobenzazoles with Carbamates, Alcohols, and Ethers
A. Lipp, G. Lahm, T. Opatz
J. Org. Chem. 2016, 81, 4890-4897.


Absolute configuration of the synthetic cannabinoid MDMB-CHMICA with its chemical characteristics in illegal products
L. Andernach, S. Pusch, C. Weber, D. Schollmeyer, S. Münster-Müller, M. Pütz, T. Opatz, Forensic Toxicol. 2016, 34, 344-352.


3,4-Dihydro-2H-pyrrole-2-carbonitriles – Useful Intermediates in the Synthesis of Fused Pyrroles
and 2,2’-Bipyrroles
M. M. Nebe, M. Kücükdisli, T. Opatz
J. Org. Chem 2016, 81, 4112-4121.


A Photoinduced Cobalt-Catalyzed Synthesis of Pyrroles through In-Situ Generated Acylazirines
S. Pusch, D. Kowalczyk, T. Opatz, J. Org. Chem. 2016, 81, 4170-4178.


A Surprising Switch in Absolute Configuration of Anti-Inflammatory Macrolactones
J. Tauber, M. Rohr, T. Walter, D. Schollmeyer, K. Rahn-Hotze, G. Erkel, T. Opatz
Org. Biomol. Chem. 2016, 14, 3695-3698.


A Short Synthesis of Pyridines from Deprotonated α-Aminonitriles by an Alkylation/RCM Sequence
C. Weber, M. M. Nebe, L. P. V. Kaluza, T. Opatz
Z. Naturforsch. B 2016, 71, 633-641.


Antifungal Paenibacillus Strains, Fusaricidin-Type Compounds, and their Use.
I. Siepe, H. Brüser, K. Klappach, K.-H. Schneider, P. Spröte, K. Hage, B. Blanz, E. Thines, L. Antelo, L. P. Sandjo, T. Opatz
PCT Int. Appl. 2016, WO2016020371.


Synthesis of 1,2-Disubstituted Indoles from α-Aminonitriles and 2-Halobenzyl Halides
A.-K. Bachon, T. Opatz
J. Org. Chem. 2016, 81, 1858-1869.


A Modular Formal Total Synthesis of (±)-Cycloclavine
N. Netz, T. Opatz
J. Org. Chem 2016, 81, 1723-1730.


A Highly Active System for the Metal-Free Aerobic Photocyanation of Tertiary Amines with Visible Light: Application to the Synthesis of Tetraponerines and Crispine A
J. C. Orejarena Pacheco, A. Lipp, A. M. Nauth, F. Acke, J.-P. Dietz, T. Opatz
Chem. Eur. J. 2016, 22, 5409-5415.


Marine Isonitriles and Their Related Compounds
J. Emsermann, U. Kauhl, T. Opatz
Marine Drugs 2016, 14, 16.


A Short Synthesis of 2,3,5-Trisubstituted Pyrroles by an Alkylation/Dehydrocyanation Sequence
M. Kücükdisli, M. M. Nebe, S. M. Bartelt, T. Opatz
Heterocycles 2016, 93, 378–390.


Total Synthesis of (–)-Hymenosetin
U. Kauhl, L. Andernach, S. Weck, L. Sandjo, S. Jacob, E. Thines, T. Opatz
J. Org. Chem. 2016, 81, 215-228.
Synfacts 2016, 12, 224.


Total Synthesis of (±)-Scopolamine: Challenges of the Tropane Ring
P.-A. Nocquet, T. Opatz
Eur. J. Org. Chem. 2016, 1156-1164.


132. Selective C–H-Activation of Methoxy Groups in a Three-Component Photoreaction
G. Lahm, T. Opatz
J. Org. Chem. 2015, 80, 12711-12717.

131. Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from Ambrosia maritima against multidrug-resistant cancer cells
M. Saeed, S. Jacob, L. Sandjo, Y. Sugimoto, H. Khalid, T. Opatz, E. Thines, T. Efferth
Front. Pharmacol. 2015, 6, 267.

130. Synthesis of Lamellarin D Trimethyl Ether and Lamellarin H via 6π-Electrocyclization
C. Dialer, D. Imbri, S. Hansen, T. Opatz
J. Org. Chem. 2015, 80, 11605-11610.

129. α-Cyanation of Aromatic Tertiary Amines using Ferricyanide as a Non-toxic Cyanide Source
A. M. Nauth, N. Otto, T. Opatz
Adv. Synth. Catal. 2015, 357, 3424-3428.

128. Xylochemistry - Making Natural Products Entirely from Wood
D. Stubba, G. Lahm, M. Geffe, J. W. Runyon, A. J. Arduengo III, T. Opatz
Angew. Chem. 2015, 127, 14394-14396 (Titelbild).
Angew. Chem. Int. Ed. 2015, 54, 14187-14189 (Cover Picture).

127. Carbohydrate nanocarriers in biomedical applications: functionalization and construction
B. Kang, T. Opatz, K. Landfester, F. R. Wurm
Chem. Soc. Rev. 2015, 44, 8301-8325.

126. Marine Indole Alkaloids
N. Netz, T. Opatz
Mar. Drugs 2015, 13, 4814-4915.

125. Total Synthesis of two Potent Anti-Inflammatory Macrolactones of the Oxacyclododecindione Type
J. Tauber, M. Rohr, T. Walter, G. Erkel, T. Opatz
Org. Biomol. Chem. 2015, 13, 7813-7821.

124. Antifungal Penicillium strains, fungicidal extrolites thereof, and their use
I. Siepe, T. Jabs, A. Schüffler, E. Thines, H. Anke, T. Opatz, L. P. Sandjo
PCT Int. Appl. 2015, WO 2015067800.

123. Enantioselective Synthesis of α-Quaternary Amino Acids by Alkylation of Deprotonated α-Aminonitriles
I. Netz, M. Kücükdisli, T. Opatz
J. Org. Chem. 2015, 80, 6864-6869.

122. Synthesis and Isolation of Enantiomerically Enriched Cyclopenta[b]benzofurans based on Products from Anodic Oxidation of 2,4-Dimethylphenol
M. Mirion, L. Andernach, C. Stobe, J. Barjau, D. Schollmeyer, T. Opatz, A. Lützen, S. R. Waldvogel
Eur. J. Org. Chem. 2015, 4876-4882.

121. Carbohydrate-Based Nanocarriers Exhibiting Specific Cell Targeting with Minimum Influence from the Protein Corona
B. Kang, P. Okwieka, S. Schöttler, S. Winzen, J. Langhanki, K. Mohr, T. Opatz, V. Mailänder, K. Landfester, F. R. Wurm
Angew. Chem. 2015, 127, 7544-7548.
Angew. Chem. Int. Ed. 2015, 54, 7436-7440.

120. Synthetic Approaches to Anti-Inflammatory Macrolactones of the Oxacyclododecindione Type
J. Tauber, K. Rudolph, M. Rohr, G. Erkel, T. Opatz
Eur. J. Org. Chem. 2015, 3587-3608.

119. Synthesis of (−)-Cryptopleurine by Combining Gold(I)-Catalysis with a Free Radical Cyclization
A. Stoye, T. Opatz
Eur. J. Org. Chem. 2015, 2149-2156.

118. A One-Pot Cascade to Protoberberine Alkaloids via Stevens-Rearrangement of Nitrile-stabilized Ammonium Ylides
G. Lahm, J-G. Deichmann, A. Rauen, T. Opatz
J. Org. Chem. 2015, 80, 2010-2016.

117. 4-Dechloro-14-deoxy-oxacyclododecindione and 14-Deoxy-oxacylododecindione, two Inhibitors of
Inducible Connective Tissue Growth Factor Expression from the Imperfect Fungus Exserohilum rostratum

J. Richter, L. P. Sandjo, J. C. Liermann, T. Opatz, G. Erkel
Bioorg. Med. Chem. 2015, 23, 556-563.

116. 2-Aminoacetonitrile
J. Tauber, T. Opatz
Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons, Ltd, 2015, DOI: 10.1002/047084289X.rn01752.


115. Synthetic Approaches to the Lamellarins - A Comprehensive Review
D. Imbri, J. Tauber, T. Opatz
Mar. Drugs 2014, 12, 6142-6177.

114. One-pot Synthesis of Pyrrole-2-carboxylates and -carboxamides via an Electrocyclization/Oxidation Sequence
D. Imbri, N. Netz, M. Kücükdisli, L. Kammer, P. Jung, A. Kretzschmann, T. Opatz
J. Org. Chem. 2014, 79, 11750-11758.

113. Total Synthesis and Biological Evaluation of the Natural Product (–)-Cyclonerodiol, a New Inhibitor of IL-4 Signaling
J. Langhanki, K. Rudolph, G. Erkel, T. Opatz
Org. Biomol. Chem. 2014, 12, 9707-9715.

112. Total Synthesis of Oxalicumone C and Elucidation of its Absolute Configuration
C. Wink, L. Andernach, T. Opatz, S. R. Waldvogel
Eur. J. Org. Chem. 2014, 7788-7792.

111. A Photochemical One-Pot Three-Component Synthesis of Tetrasubstituted Imidazoles
S. Pusch, T. Opatz
Org. Lett. 2014, 16, 5430-5433.

110. Radical Addition to Iminium Ions and Cationic Heterocycles
J. Tauber, D. Imbri, T. Opatz
Molecules 2014, 19, 16190-16222.

109. Enantioselective Synthesis of (–)-Dihydrocodeine and Formal Synthesis of
(–)-Thebaine, (–)-Codeine, and (–)-Morphine from a Deprotonated α-Aminonitrile
M. Geffe, T. Opatz
Org. Lett. 2014, 16, 5282-5285.

108. Fungicidal naphthoquinones and derivates
C. Wiebe, J. Reinheimer, D. Kremzow-Graw, F. Roehl, S. Schwolow, T. Opatz, A. Schueffler, H. Kunz, E. Thines
PCT Int. Appl. 2014, WO 2014118099.

107. Heterocycles from α-Aminonitriles (Concept article)
N. Otto, T. Opatz
Chem. Eur. J. 2014, 20, 13064-13077.

106. Unique Regioselectivity in the C(sp3)–H α-Alkylation of Amines:
The Benzoxazole Moiety as a Removable Directing Group
G. Lahm, T. Opatz
Org. Lett 2014, 16, 4201-4203.

105. Excelsoside: A new Benzylic Diglycoside from the Leaves of Milicia excelsa
J. L. N. Ouete, L. P. Sandjo, D. W. F. G. Kapche, S. O. Yeboah, R. Mapitse, B. M. Abegaz, T. Opatz, B. T. Ngadjui
Z. Naturforsch. C 2014, 69, 271-275.

104. A Two-step Synthesis of 2-Aminoindolizines from 2-Alkylpyridines
M. Kücükdisli, T. Opatz
Eur. J. Org. Chem. 2014, 5836-5844.

103. Rearrangements of Nitrile-stabilized Ammonium Ylides
G. Lahm, J. C. Orejarena Pacheco, T. Opatz
Synthesis 2014, 46, 2413-2421.

102. Elatumic Acid: A New Ursolic Acid Congener from Omphalocarpum elatum Miers (Sapotaceae)
L. P. Sandjo, C. G. Fru, V. Kuete, F. Nana, S. O. Yeboah, R. Mapitse, B. M. Abegaz, T. Efferth, T. Opatz
Z. Naturforsch. C 2014, 69, 276-282.

101. Assignment of the Absolute Configuration and Total Synthesis of (+)-Caripyrin
L. Andernach, T. Opatz
Eur. J. Org. Chem. 2014, 22, 4780-4784.

100. Ring Expansion of 1,2,3,4-Tetrahydroisoquinolines to Dibenz[c,f]azonines. An Unexpected
[1,4]-Sigmatropic Rearrangement of Nitrile-Stabilized Ammonium Ylides.
J. C. Orejarena Pacheco, T. Opatz
J. Org. Chem. 2014, 79, 5182-5192.

99. Anti-inflammatory drimane sesquiterpene lactones from an Aspergillus species
S. Felix, L. P. Sandjo, T. Opatz, G. Erkel
Bioorg. Med. Chem. 2014, 22, 2912-2918.

98. Zugänge zu Isomeren und Verwandten der Lamellarin-Alkaloide
J. Tauber, D. Imbri, V. C. Colligs, T. Opatz
Z. Naturforsch. B 2014, 69, 627-640.

97. Chemoenzymatic Synthesis of Functional Sialyl Lewisx-Mimetics with a Heteroaromatic Core
C. Schlemmer, C. Wiebe, D. Ferenc, D. Kowalczyk, S. Wedepohl, P. Ziegelmüller, J. Dernedde, T. Opatz
Chem. Asian J. 2014, 9, 2119-2125.

96. Chromatographically Separable Rotamers of an Unhindered Amide
M. Geffe, L. Andernach, O. Trapp, T. Opatz
Beilstein J. Org. Chem. 2014, 10, 701-706.

95. Simple Two-Step Synthesis of 2,4-Disubstituted Pyrroles and 3,5-Disubstituted Pyrrole-2-carbonitriles from Enones
M. Kücükdisli, D. Ferenc, M. Heinz, C. Wiebe, T. Opatz
Beilstein J. Org. Chem. 2014, 10, 466-470.

94. Tanzawaic acids I-L: Four New Polyketides from Penicillium sp. IBWF104-06
L. P. Sandjo, E. Thines, T. Opatz, A. Schüffler
Beilstein J. Org. Chem. 2014, 10, 251-258.

93. Synthetic approaches towards huperzine A and B
S. M. A. Sohel, T. Opatz
Arkivoc 2014 (i), 92-108.


92. SF002-96-1, a New Drimane Sesquiterpene Lactone from an Aspergillus Species, Inhibits Survivin Expression
S. Felix, L. P. Sandjo, T. Opatz, G. Erkel
Beilstein J. Org. Chem. 2013, 9, 2866-2876.

91. A High Yielding Modular Access to the Lamellarins: Synthesis of Lamellarin G
Trimethylether, Lamellarin η and Dihydrolamellarin η
D. Imbri, J. Tauber, T. Opatz
Chem. Eur. J. 2013, 19, 15080-15083.

90. New tracer compounds for secondary organic aerosol formation from β-caryophyllene
A. van Eijck, T. Opatz, D. Taraborrelli, R. Sander, T. Hoffmann
Atmos. Environ. 2013, 80, 122-130.

89. Omphalocarpoidone, a New Lanostane-type Furano-spiro-γ-Lactone from the wood of
Tridesmostemon omphalocarpoides Engl. (Sapotaceae)
C. G. Fru, L. P. Sandjo, V. Kuete, J. C. Liermann, D. Schollmeyer, T. Opatz, B. T. Ngadjui
Phytochem. Lett. 2013, 6, 676-680.

88. Total Synthesis of the Antifungal Natural Product Mollisin
S. Schwolow, H. Kunz, J. Rheinheimer, T. Opatz
Eur. J. Org. Chem. 2013, 6519-6524.

87. A New Flavone from the Roots of Milicia excelsa (Moraceae)
J. L. Nantchouang Ouete, L. P. Sandjo, D. W. F. G. Kapche, J. C. Liermann, T. Opatz, I. K. Simo,
B. T. Ngadjui
Z. Naturforsch. C 2013, 68, 259-263.

86. One-Pot Synthesis of Polysubstituted Indolizines by an Addition/Cycloaromatization
M. Kücükdisli, T. Opatz
J. Org. Chem. 2013, 78 (13), 6670-6676.

85. Configurational Assignment of a Series of Dioxolane-Type Secondary Metabolites
from Guignardia bidwellii - A comparison of VCD and ECD Spectroscopy
L. Andernach, L. P. Sandjo, J. C. Liermann, I. Buckel, E. Thines, T. Opatz
Eur. J. Org. Chem. 2013, 5946-5951.

84. Total Synthesis of (+)-Phenguignardic Acid, A Phytotoxic Metabolite of Guignardia
A. Stoye, D. Kowalczyk, T. Opatz
Eur. J. Org. Chem. 2013, 5952-5960.

83. Synthesis of Highly Substituted 2-13C-Imidazolium Salts and Metal NHC Complexes
for the Investigation of Electronic Unsymmetry by NMR
J. Emsermann, A. J. Arduengo III, T. Opatz
Synthesis 2013, 45, 2251-2264.

82. Synthesis of Alkaloids by Stevens Rearrangement of Nitrile-Stabilized Ammonium
Ylides: (±)-Laudanosine, (±)-Laudanidine, (±)-Armepavine,
(±)-7-Methoxycryptopleurine, and (±)-Xylopinine
J. C. Orejarena Pacheco, G. Lahm, T. Opatz
J. Org. Chem. 2013, 78 (10), 4985-4992.

81. Phytotoxic dioxolanone-type secondary metabolites from Guignardia bidwellii
I. Buckel, D. Molitor, J. C. Liermann, L. P. Sandjo, B. Berkelmann-Löhnertz, T. Opatz, E. Thines
Phytochemistry 2013, 89, 96-103.

80. Left, Right, or Both? On the Configuration of the Phenanthroindolizidine Alkaloid
Tylophorine from Tylophora indica

A. Stoye, T. E. Peez, T. Opatz
J. Nat. Prod. 2013, 76 (2), 275-278.


79. The Iodocyclization of o-Alkynylbenzamides Revisited: Formation of
Isobenzofuran-1(3H)-imines and 1H-Isochromen-1-imines instead of Lactams
C. Schlemmer, L. Andernach, D. Schollmeyer, B. F. Straub, T. Opatz
J. Org. Chem. 2012, 77, 10118-10124.

78. Drimane sesquiterpenoids from Marasmius sp. inhibiting the conidial
germination of plant-pathogenic fungi
J. Liermann, E. Thines, T. Opatz, H. Anke
J. Nat. Prod. 2012, 75, 1983-1986.

77. (2E,4R,5R,6S)-2-(4,5,6-Trihydroxycyclohex-2-en-1-ylidene)acetonitrile
A. N. Guedem, L. P. Sandjo, T. Opatz, D. Schollmeyer and B. T. Ngadjui
Acta Cryst. 2012, E68, o2737.

76. A Five-Step Synthesis of (±)-Tylophorine via a Nitrile-stabilized Ammonium Ylide
G. Lahm, A. Stoye, T. Opatz
J. Org. Chem. 2012, 77, 6620-6623.

75. Screening of ligands for the Ullmann synthesis of electron rich diaryl ethers
N. Otto, T. Opatz
Beilstein J. Org. Chem. 2012, 8, 1105-1111.

74. Phenguignardic Acid and Guignardic Acid, Phytotoxic Secondary Metabolites from
Guignardia bidwellii
D. Molitor, J. C. Liermann, B. Berkelmann-Löhnertz, I. Buckel, T. Opatz, E. Thines
J. Nat. Prod. 2012, 75, 1265-1269.

73. Isolactarane and Sterpurane Sesquiterpenoids from the Basidiomycete Phlebia uda
A. Schüffler, B. Wollinsky, T. Anke, J. C. Liermann, T. Opatz
J. Nat. Prod. 2012, 75, 1405-1408.

72. Gems from traditional north-African medicine: medicinal and aromatic plants from
H. Khalid, W. E. Abdalla, H. Abdelgadir, T. Opatz, T. Efferth
Nat. Prod. Bioprospect. 2012, 2, 92-103.

71. A Modular Synthesis of Polysubstituted Indolizines
M. Kücükdisli, T. Opatz
Eur. J. Org. Chem. 2012, 4555-4564.

70. 3'-Demethyldihydromaldoxin and Dihydromaldoxin, two anti-inflammtorydiaryl ethers
from a Steganospora species
G. Erkel, D. Schreiber, M. Jung, L. P. Sandjo, J. C. Liermann, T. Opatz
J. Antibiot. 2012, 65, 473-477.

69. Donellanic acids A–C: new cyclopropanic oleanane derivatives from Donella
ubanguiensis (Sapotaceae)
A. V. B. Djoumessi, L. P. Sandjo, J. C. Liermann, D. Schollmeyer,V. Kuete, V. Rincheval,
A. M. Berhanue, S. O. Yeboah, P. Wafo, B. T.Ngadjui, T. Opatz
Tetrahedron 2012, 68(24), 4621-4627.

68. Coumarin derivatives from Pedilanthus tithymaloides as inhibitors of conidial
germination in Magnaporthe oryzae
L. P. Sandjo, A. J. Foster, J. Rheinheimer, H. Anke, T. Opatz, E. Thines
Tetrahedron 2012, 53(17), 2153-2156.

67. Unexpected Formation of a 1,2-Dichloroacenaphthylene in a Friedel-Crafts Reaction
with Chloral Hydrate
S. Schwolow, D. Schollmeyer, T. Opatz
Z. Naturforsch. B 2012, 67, 272-274.

66. Synthesis of 1,3- and 2,3- Diglycosylated Indoles as Potential Trisaccharide Mimetics
C. Wiebe, S. Fusté de la Sotilla, T. Opatz
Synthesis 2012, 44, 1385-1397.

65. The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide
excision repair-deficient cells

R. Abbasi, T. Efferth, C. Kuhmann, T. Opatz, X. Hao, O. Popanda, P. Schmezer
Toxicol. Appl. Pharmacol. 2012, 259(3), 302-310 .

64. Monosaccharidic Mimetics of the Sialyl Lewis X Tetrasaccharide basedon

S. Weck, M. Frank, A. Hamann, T. Opatz
ARKIVOC 2012 (iii), 134-148.

63. Microwave-Assisted Synthesis of 1,3-Disubstituted β-Carbolines from
and Gramine
J. Letessier, H. Detert, K. Götz, T. Opatz
Synthesis 2012, 747-754.

62. GKK1032A2, a secondary metabolite from Penicillium sp. IBWF-029-96, inhibits
conidial germination in the rice blast fungus Magnaporthe oryzae

J. Becker, J. C. Liermann, T. Opatz, H. Anke, E. Thines
J. Antibiot. 2012, 65, 99-102.


61. (rac)-4-[(E)-{[1-Cyano-1-cyclohexyl-2-(1H-indol-3-yl)ethyl]imino}methyl]benzonitrile
J. Letessier, D. Schollmeyer, H. Detert, T. Opatz
Acta Cryst. 2011, E67, o3435.

60. Enantioselective Synthesis of Tetrahydroprotoberberines and
Bisbenzylisoquinoline Alkaloids from a Deprotonated alpha-Aminonitrile

N. Blank, T. Opatz
J. Org. Chem. 2011, 76, 9777-9784.

59. 1,3-Benzyl Migration in Iminium Ions – Evidence for a Fast Free Radical Chain

N. Blank, B. F. Straub, T. Opatz
Eur. J. Org. Chem. 2011, 7355-7365.

58. Ganodermycin, a Novel Inhibitor of CXCL10 Expression from Ganoderma applanatum
G. Erkel, M. Jung, J. C. Liermann, T. Opatz
J. Antibiot. 2011, 64, 683-686.

57. Sweet (hetero)aromatics: glycosylated templates for the construction of saccharide

C. Wiebe, C. Schlemmer, S.Weck, T. Opatz
Chem. Comm. 2011, 47, 9212-9214.

56. Pyrroles and Indolizidines from Deprotonated α-(Alkylideneamino)nitriles
I. Schäfer, T. Opatz
Synthesis 2011, 1691-1704.

55. Elucidation of the Biosynthesis and Degradation of Allantofuranone by
Isotopic Labelling and Fermentation of Modified Precursors

A. Schüffler, J. C. Liermann, T. Opatz, T. Anke
ChemBioChem. 2011, 148-154.


54. N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide

C. Schlemmer, D. Schollmeyer, N. Blank, A. Stoye, T. Opatz
Acta Cryst. 2010, E66, o3343.

53. Microwave-Assisted Synthesis of Polysubstituted 4-Quinolones from Deprotonated

A. Romek, T. Opatz
Eur. J. Org. Chem. 2010, 30, 5841-5849.

52 Synthesis of Bioactive 2-Aza Analogues of Ipecac and Alangium Alkaloids
M. Kölzer, K. Weitzel, H. U. Göringer, E. Thines, T. Opatz
ChemMedChem. 2010, 5, 1456-1464.

51. Racemization-Free Synthesis of (S)-(+)-Tylophorine from L-Proline
A. Stoye, T. Opatz
Org. Lett. 2010, 12, 2140-2141.
Synfacts 2010, 979.

50. β-Selective C-Mannosylation of electron rich Phenols
S. Weck, T. Opatz
Synthesis 2010, 14, 2393-2398.

49. Hirsutane-Type Sesquiterpenes with Uncommon Modifications from Three

J. C. Liermann, A. Schüffler, B. Wollinsky, J. Birnbacher, H. Kolshorn, T. Anke, T. Opatz
J. Org. Chem. 2010, 75, 2955-2961.

48. Caripyrin, a new inhibitor of infection-related morphogenesis in the rice
blast fungus Magnaporthe oryzae

P. H. Rieger, J. C. Liermann, T. Opatz, H. Anke, E. Thines
J. Antibiot. 2010, 63, 285-289.

47. Structure Elucidation of Hypocreolide A by Enantioselective Total Synthesis
K. Götz, J. C. Liermann, E. Thines, H. Anke, T. Opatz
Org. Biomol. Chem. 2010, 2123-2130.


46. Z-Amino(2-methyl-3-oxoisoindolin-1-ylidene)acetonitrile
D. Schollmeyer, D. Ferenc, T. Opatz
Acta Cryst. 2009, E65, o3024.

45. Xanthepinone, an Antimicrobial Polyketide from a Soil Fungus Closely
Related to Phoma medicaginis

J. C. Liermann, H. Kolshorn, T. Opatz, E. Thines, H. Anke
J. Nat. Prod. 2009, 72, 1905-1907.

44. Cyclocondensation of α-Aminonitriles and Enones – a Short Access to 3,4-
Dihydro-2H-pyrrole 2-carbonitriles and 2,3,5-Trisubstituted Pyrroles

I. Bergner, C. Wiebe, N. Meyer, T. Opatz
J. Org. Chem. 2009, 74, 8243-8253.

43. Sfp-type 4’-phosphopantetheinyl transferase is indispensable for fungal

R. Horbach, A. Graf, F. Weihmann, L. Antelo, S. Mathea, J. C. Liermann, T. Opatz, E. Thines, J.
Aguirre, H. B. Deising
Plant Cell 2009, 21, 3379-3396.

42. New caloporoside derivatives and their inhibition of fungal spore germination
A. Schüffler, J. C. Liermann, H. Kolshorn, T. Opatz, T. Anke
Z. Naturforsch. C 2009, 64, 521-525.

41. Isolation, structure elucidation and biological evaluation of the unusual
heterodimer chrysoxanthone from the ascomycete IBWF11-95A

A. Schüffler, J. C. Liermann, H. Kolshorn, T. Opatz, H. Anke
Tetrahedron Lett. 2009, 50, 4813-4815.

40. Anthranicine, an Unusual Cyclic Hexapeptide from Acremonium sp. A29-2004
J. C. Liermann, E. Thines, H. Anke, T. Opatz
Z. Naturforsch. B 2009, 64, 727-730.

39. The Chemistry of Deprotonated α-Aminonitriles (Review)
T. Opatz
Synthesis 2009, 1941-1959.

38. Omphalotins E-I, Five Oxidatively Modified Nematicidal Cyclopeptides
from Omphalotus olearius

J. C. Liermann, T. Opatz, H. Kolshorn, L. Antelo, C. Hof, H. Anke
Eur. J. Org. Chem. 2009, 1256-1262.

37. Allantofuranone, a New Antifungal Antibiotic from Allantophomopsis
lycopodina IBWF58B-05A

A. Schüffler, D. Kautz, J. C. Liermann, T. Opatz, T. Anke
J. Antibiot. 2009, 62, 119-121.

36. New Naphthoquinone Derivatives from the Ascomycete IBWF79B-90A
A. Schüffler, J. C. Liermann, H. Kolshorn, T. Opatz, H. Anke
Z. Naturforsch. C 2009, 64, 25-31.

35. Modular Synthesis of Tetrasubstituted Imidazoles and Trisubstituted
Oxazoles by Aldimine Cross Coupling

C. Kison, T. Opatz
Chem. Eur. J. 2009, 15, 843-845.
Synfacts 2009, 377.


34. Ascomycones
T. Opatz, H. Kolshorn, E. Thines, H. Anke
J. Nat. Prod. 2008, 71, 1973-197.

33. Synthesis of the CDK-Inhibitor Paullone by Cyclization of a Deprotonated
T. Opatz, D. Ferenc
Synthesis 2008, 3941-3944.

32. Sterelactones: new isolactarane type sesquiterpenoids with antifungal
activity from Stereum sp. IBWF 01060

T. Opatz, H. Kolshorn, H. Anke
J. Antibiot. 2008, 61, 563-567.

31. Tetracyclic Terpenoids from Dasyscyphus niveus, Dasyscyphins D and E
J. C. Liermann, H. Kolshorn, H. Anke, E. Thines, T. Opatz
J. Nat. Prod. 2008, 71, 1654-1656.

30. Synthesis of Lamellarin U and Lamellarin G Trimethyl Ether by
Alkylation of a Deprotonated α-Aminonitrile

J. C. Liermann, T. Opatz
J. Org. Chem. 2008, 73, 4526-4531.

29. Oxacyclododecindione, a novel inhibitor of IL-4 signaling from
Exserohilum rostratum

G. Erkel, H. Belahmer, A. Serwe, T. Anke, H. Kunz, H. Kolshorn, J. Liermann, T. Opatz
J. Antibiot. 2008, 61, 285-290.

28. Isolation and biological activity of new norhirsutanes from Creolophus

J. Birnbacher, A. Schueffler, F. Deininger, T. Opatz, T. Anke
Z. Naturforsch. C 2008, 63, 203-206.

27. One-pot synthesis of trisubstituted 1,2-amino alcohols from deprotonated
α-amino nitriles

C. Kison, T. Opatz
Eur. J. Org. Chem. 2008, 2740-2745.


26. The creolophins: a family of linear triquinanes from Creolophus cirrhatus

T. Opatz, H. Kolshorn, J. Birnbacher, A. Schuffler, F. Deininger, T. Anke
Eur. J. Org. Chem. 2007, 5546-5550.

25. A Modular One-Pot Synthesis of Tetrasubstituted Pyrroles from
I. Bergner, T. Opatz
J. Org. Chem. 2007, 72, 7083-7090.

24. Synthesis of (-)-(S)-Norlaudanosine, (+)-(R)-O,O-Dimethylcoclaurine, and
(+)-(R)-Salsolidine by Alkylation of an α-Aminonitrile

F. Werner, N. Blank, T. Opatz
Eur. J. Org. Chem. 2007, 3911-3915.

23. Synthesis of γ-Amino Acid Esters via 1,4-Addition of Deprotonated α-
Aminonitriles and α-(Alkylideneamino)nitriles to α,β-Unsaturated Esters

I. Bergner, T. Opatz
Synthesis 2007, 918-928.


22. Preparation of indoles from α-aminonitriles: a short synthesis of FGIN-1-27
T. Opatz, D. Ferenc
Org. Lett. 2006, 8, 4473-447.

21. Synthesis of Highly Substituted Unsymmetrical 1,2-Diamines, 1,2-
Diimines, Imidazolium Salts and Imidazolylidenes by Aldimine Cross-Coupling
C. Kison, T. Opatz
Synthesis 2006, 3727-3738.

20. One-pot synthesis of (±)-crispine A and its C-ring-substituted analogs
N. Meyer, T. Opatz
Eur. J. Org. Chem. 2006, 3997-4002.

19. Ring contracting rearrangements of 3-amino-4-(arylamino)-1H-isochromen-1-ones
T. Opatz, D. Ferenc
Eur. J. Org. Chem. 2006, 121-126.


18. An Aldimine Cross-Coupling for the Diastereoselective Synthesis of
Unsymmetrical 1,2-Diamines

C. Kison, N. Meyer, T. Opatz
Angew. Chem., Int. Ed. 2005, 44, 5662-5664.

17. One-pot Synthesis of Polysubstituted Pyrrolidines from Aminonitriles
N. Meyer, F. Werner, T. Opatz
Synthesis 2005, 945-956.

16. Facile preparation of 3-amino-4-(arylamino)-1H-isochromen-1-ones by a
new multicomponent reaction

T. Opatz, D. Ferenc
Eur. J. Org. Chem. 2005, 817-821.


15. An unexpected three-component condensation leading to amino-(3-oxo-

T. Opatz, D. Ferenc
J. Org. Chem. 2004, 69, 8496-8499.

14. Synthesis of two Conformationally Restricted Piperazine Scaffolds for
Combinatorial Chemistry

T. Opatz
Eur. J. Org. Chem. 2004, 4113-4118.

13. Combinatorial synthesis of amino acid- and peptide-carbohydrate
conjugates on solid phase

T. Opatz, C. Kallus, T. Wunberg, H. Kunz
Tetrahedron 2004, 60, 8613-8626.

12. A short synthesis of polysubstituted pyrrolidines via α-

N. Meyer, T. Opatz
Synlett 2004, 787-790.

Ältere Publikationen

11. Addition of α-aminonitriles to α,β-unsaturated carbonyl compounds: A
one-pot synthesis of polysubstituted pyrrolidines

N. Meyer, T. Opatz
Synlett 2003, 1427-1430.

10. D-Glucose as a pentavalent chiral scaffold
T. Opatz, C. Kallus, T. Wunberg, W. Schmidt, S. Henke, H. Kunz
Eur. J. Org. Chem. 2003, 1527-1536.

09. D-glucose as a multivalent chiral scaffold for combinatorial chemistry
T. Opatz, C. Kallus, T. Wunberg, W. Schmidt, S. Henke, H. Kunz
Carbohydr. Res. 2002, 337, 2089-2110.

08. Synthesis and screening of libraries of synthetic tripodal receptor
molecules with three different amino acid or peptide arms: Identification

of iron binders
T. Opatz, R. M. J. Liskamp
J. Comb. Chem. 2002, 4, 275-284.

07. A selectively deprotectable triazacyclophane scaffold for the construction
of artificial receptors

T. Opatz, R. M. J. Liskamp
Org. Lett. 2001, 3, 3499-3502.

06. A facile cleavage of allyl ethers on solid phase
T. Opatz, H. Kunz
Tetrahedron Lett. 2000, 41, 10185-10188.

05. Combinatorial solid-phase synthesis using D-Galactose as a chiral five-
dimension-diversity scaffold

C. Kallus, T. Opatz, T. Wunberg, W. Schmidt, S. Henke, H. Kunz
Tetrahedron Lett. 1999, 40, 7783-7786.

04. Substituted tetrahydropyrane derivatives, method for producing same,
their use as medicine or diagnostic agent, as well as medicine containing

S. Henke, H. Kunz, T. Opatz, T. Wunberg, C. Kallus, W. Schmidt
PCT Int. Appl. 1999, WO9907718.

03. Carbohydrates as multifunctional chiral scaffolds in combinatorial

T. Wunberg, C. Kallus, T. Opatz, S. Henke, W. Schmidt, H. Kunz
Angew. Chem., Int. Ed. 1998, 37, 2503-2505.

02. New ventures in the construction of complex heterocycles: Synthesis of
morphine and hasubanan alkaloids

D. Trauner, S. Porth, T. Opatz, J. W. Bats, G. Giester, J. Mulzer
Synthesis 1998, 653-664.

01. The phenanthrenone approach to opium alkaloids: Formal total synthesis
of morphine by sigmatropic rearrangement

J. Mulzer, J. W. Bats, B. List, T. Opatz, D. Trauner
Synlett 1997, 441-444.

Buchbesprechungen, Tagungsberichte

04. Quaternary Stereocenters - Challenges and Solutions for Organic Synthesis
Herausgegeben von J. Christoffers, A. Baro
T. Opatz
Adv. Synth. Catal. 2006, 348, 593.

03. Glycoscience
Herausgegeben von Bertram Fraser-Reid, Kuniaki Tatsuta und Joachim Thiem.
T. Opatz, H. Kunz
Angew. Chem. 2003, 115, 23.

02. Handbook of Combinatorial Chemistry - Drugs, Catalysts, Materials
Herausgegeben von K. C. Nicolaou, R. Hanko und W. Hartwig.
H. Kunz, T. Opatz
J. Chem. Soc., Perkin Trans. 1, 2002, 2730.

01. Bürgenstock: Stereochemie ohne Grenzen
R. Haag, T. Opatz
Nachr. Chem. 2002, 50, 830-834.